ENDOMETRIN is a vaginal insert that contains the hormone progesterone. ENDOMETRIN is for women who need extra progesterone while undergoing treatment in an assisted reproductive technology (ART) cycle.
Progesterone is one of the hormones essential for helping you to become and to stay pregnant. If you are undergoing ART treatment, your doctor may prescribe ENDOMETRIN to provide the progesterone your body needs.
In a US IVF trial with more than 1200 patients, ENDOMETRIN was proven effective.
Each ENDOMETRIN insert supplies 100 mg of progesterone and comes with its own single-use disposable applicator for sterile insertion into the vagina, 2 or 3 times a day, for up to 10 weeks, as your doctor prescribes.
ENDOMETRIN can be inserted while you are standing, sitting, or lying on your back with your knees bent.
Progesterone is one of the hormones essential for helping you to become and to stay pregnant. If you are undergoing ART treatment, your doctor may prescribe ENDOMETRIN to provide the progesterone your body needs.
Common side effects seen with ART and Endometrin included pelvic pain after surgery, abdominal pain, nausea, and swollen ovaries (ovarian hyperstimulation syndrome). Other reported side effects included abdominal bloating, headache, urinary infections, uterine cramping, constipation, vomiting, tiredness, and vaginal bleeding. Vaginal products with progesterone may also cause vaginal irritation, burning and discharge.
These are not all the possible side effects of ENDOMETRIN. For more information, ask your healthcare provider or pharmacist.
Tell your healthcare provider if you have any side effect that bothers you or that does not go away.
Click here to review Important Safety Information and also full Prescribing Information, including Patient Information.
ENDOMETRIN® (progesterone) is a vaginal insert that contains the hormone progesterone, one of the hormones essential for helping you to become and to stay pregnant. ENDOMETRIN is for women who need extra progesterone while undergoing treatment in an Assisted Reproductive Technology (ART) program.
Do not use ENDOMETRIN if you:
Common side effects seen with ART and ENDOMETRIN include pelvic pain after surgery, abdominal pain, nausea, and swollen ovaries (ovarian hyperstimulation syndrome). Other reported side effects include abdominal bloating, headache, urinary infections, uterine cramping, constipation, vomiting, tiredness and vaginal bleeding. Vaginal products with progesterone may also cause vaginal irritation, burning and discharge.
Progesterone can increase your chance of getting blood clots. Blood clots can be serious and lead to death. Serious blood clots include those in the : legs, lungs, eyes, heart, and brain.
Call your doctor and get medical help right away if you have; Persistent lower leg pain, sudden shortness of breath, coughing up blood, sudden blindness(partial or complete, severe chest pain, sudden severe headache, vomiting, dizziness, or fainting, weakness in an arm or leg, or trouble speaking, yellowing of the skin and/or white of the eyes indicating possible liver problems.
Other risks of progesterone include: Headache, breast tenderness, bloating or fluid retention, mood swings and depression, irritability and drowsiness.
Call your doctor immediately if you have abnormal vaginal bleeding.
These are not all the side effects with ENDOMETRIN. Ask your doctor or pharmacist for more information.
Tell your healthcare provider if you have any side effects that bothers you or that does not go away. You may report side effects to FDA at 1-800-FDA-1088